{"id":11625,"date":"2024-08-12T10:19:06","date_gmt":"2024-08-12T14:19:06","guid":{"rendered":"https:\/\/www.vdh.virginia.gov\/surveillance-and-investigation\/?page_id=11625"},"modified":"2025-08-14T06:13:14","modified_gmt":"2025-08-14T10:13:14","slug":"additional-resources","status":"publish","type":"page","link":"https:\/\/www.vdh.virginia.gov\/surveillance-and-investigation\/genomic-epidemiology\/additional-resources\/","title":{"rendered":"Additional Resources"},"content":{"rendered":"<div id=\"pl-11625\"  class=\"panel-layout\" ><div id=\"pg-11625-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-11625-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-11625-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h2>Definitions<\/h2>\n<p><b><span data-contrast=\"none\">Genome Sequencing:\u00a0<\/span><\/b><span data-contrast=\"none\">\u00a0A variety of laboratory procedures that provide detailed information about the genetic makeup of infectious disease pathogens (germs) that are making people sick.<\/span><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><b><span data-contrast=\"none\">Gene:\u00a0<\/span><\/b><span data-contrast=\"none\">A specific sequence of DNA or RNA found at a specific location in a genome. Each gene encodes a function within the human body or other organisms (for example<\/span><span data-contrast=\"none\">,<\/span><span data-contrast=\"none\"> there are specific genes that produce eye color).<\/span><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><b><span data-contrast=\"none\">Genome: <\/span><\/b><span data-contrast=\"none\">All of the DNA or RNA found in a cell or virus.\u00a0<\/span><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><b><span data-contrast=\"auto\">Mutation:\u00a0<\/span><\/b><span data-contrast=\"none\">A change in the genetic sequence of DNA or RNA where nucleotides have been altered, inserted, or deleted.\u00a0<\/span><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><b><span data-contrast=\"none\">Phylogenetic Tree:\u00a0<\/span><\/b><span data-contrast=\"none\"><a href=\"https:\/\/docs.nextstrain.org\/en\/latest\/learn\/interpret\/how-to-read-a-tree.html#reading-a-phylogenetic-tree\">A tree-like diagram that shows mutational differences between sequenced DNA or RNA<\/a>.\u00a0 These diagrams show evolutionary changes and genetic relationships between organisms over time.<\/span><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<figure id=\"attachment_11958\" aria-describedby=\"caption-attachment-11958\" style=\"width: 474px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-11958 \" src=\"https:\/\/www.vdh.virginia.gov\/content\/uploads\/sites\/13\/2025\/07\/toy_alignment_tree-01-copy-300x119.jpg\" alt=\"The illustration above shows a sketch of a transmission tree with a subset of cases that were sampled.\" width=\"474\" height=\"188\" srcset=\"https:\/\/www.vdh.virginia.gov\/content\/uploads\/sites\/13\/2025\/07\/toy_alignment_tree-01-copy-300x119.jpg 300w, https:\/\/www.vdh.virginia.gov\/content\/uploads\/sites\/13\/2025\/07\/toy_alignment_tree-01-copy-1024x405.jpg 1024w, https:\/\/www.vdh.virginia.gov\/content\/uploads\/sites\/13\/2025\/07\/toy_alignment_tree-01-copy-768x304.jpg 768w, https:\/\/www.vdh.virginia.gov\/content\/uploads\/sites\/13\/2025\/07\/toy_alignment_tree-01-copy.jpg 1200w\" sizes=\"auto, (max-width: 474px) 100vw, 474px\" \/><figcaption id=\"caption-attachment-11958\" class=\"wp-caption-text\">The illustration above shows a sketch of a transmission tree with a subset of cases that were sampled (A-E). The colored dots indicate mutations between samples. Source: <a href=\"https:\/\/docs.nextstrain.org\/en\/latest\/learn\/interpret\/how-to-read-a-tree.html#reading-a-phylogenetic-tree\">How to read a phylogenetic tree<\/a><\/figcaption><\/figure>\n<h2>Links to More Information<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.cdc.gov\/advanced-molecular-detection\/about\/what-is-genomic-sequencing.html#:~:text=Determining%20the%20order%20of%20bases%20is%20called%20%22genomic,bacteria,%20viruses,%20and%20fungi%20represent%20unique%20genetic%20fingerprints.\"><span data-contrast=\"none\">What is Genomic Sequencing? | AMD | CDC?<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/li>\n<li><a href=\"https:\/\/www.cdc.gov\/advanced-molecular-detection\/about\/index.html\"><span data-contrast=\"none\">What is Advanced Molecular Detection (AMD)? | AMD | CDC<\/span><\/a><span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/li>\n<li><a href=\"https:\/\/va-pgcoe.org\/\"><span data-contrast=\"none\">Virginia Pathogen Genomics Center of Excellence<\/span><\/a> <span data-ccp-props=\"{&quot;335557856&quot;:16777215,&quot;335559739&quot;:0}\">\u00a0<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Definitions Genome Sequencing:\u00a0\u00a0A variety of laboratory procedures that provide detailed information about the genetic makeup of infectious disease pathogens (germs) that are making people sick.\u00a0 \u00a0Gene:\u00a0A specific sequence of DNA or RNA found at a specific location in a genome. Each gene encodes a function within the human body or other organisms (for example, there [&hellip;]<\/p>\n","protected":false},"author":230,"featured_media":0,"parent":11577,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"tags":[],"class_list":["post-11625","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Additional Resources - Surveillance and Investigation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.vdh.virginia.gov\/surveillance-and-investigation\/additional-resources\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Additional Resources - Surveillance and Investigation\" \/>\n<meta property=\"og:description\" content=\"Definitions Genome Sequencing:\u00a0\u00a0A variety of laboratory procedures that provide detailed information about the genetic makeup of infectious disease pathogens (germs) that are making people sick.\u00a0 \u00a0Gene:\u00a0A specific sequence of DNA or RNA found at a specific location in a genome. 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